San Diego is a major city in California. It's known for its mild year-round climate, natural deep-water harbor, extensive beaches, long association with the United States Navy and recent emergence as a healthcare and biotechnology development center. San Diego's main economic engines are military and defense-related activities, tourism, international trade, and manufacturing. The presence of the University of California, San Diego (UCSD), with the affiliated UCSD Medical Center, has helped make the area a center of research in biotechnology.

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